Covid booster vaccine reawakens world's deadliest virus inside man's body | 7 March 2025 | Doctors have revealed an extremely rare case that saw the Covid vaccine reawaken a deadly virus inside a man's body. The unnamed 47-year-old had been living with a dormant tuberculosis infection that was not causing symptoms when he received his booster shot in India. Five days after vaccination, he began experiencing "severe constitutional symptoms" including fever, fatigue and night sweats. Doctors discovered that his immune system, now stronger from the vaccine, started attacking the TB infection too aggressively, causing inflammation and the flare-up of symptoms. He was diagnosed with tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS), marking the first known case linked to a Covid booster.